Exam questionKROK 1Dentistry ยท 2012
An oncological patient had been administered methotrexate. With time target cells of the tumour lost sensitivity to this drug. At the same time the change in gene expression of the following enzyme is observed:
Answer options
- Deaminase
- Dehydropholate reductase
- Pholate oxidase
- Thiaminase
- Pholate decarboxylase
Correct answer
Dehydropholate reductase
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