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Exam questionKROK 1Dentistry ยท 2014

In some areas of South Africa many people have sickle cell disease characterized by red blood cells that assume an abnormal sickle shape due to the substitution of glutamic acid for valine in the hemoglobin molecule. What is the cause of this disease?

Answer options

  1. Crossing-over
  2. Transduction
  3. Genomic mutation
  4. Gene mutation
  5. Disturbances of the mechanisms of genetic information transmission
Correct answer

Gene mutation

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