A 59-year-old man was diagnosed with a transmural left ventricular myocardial infarction. He died of a true heart rupture - cardiac tamponade. What process in the infarction site could have contributed to the cardiac rupture in this case?

Answer options

1. Autolytic processes of myocardial softening (myomalacia)
2. Scar formation with thinning of the left ventricular wall
3. Increased pressure in the pulmonary circulation
4. -
5. Replacement of the infarct site with connective tissue (organization)