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Exam questionKROK 1Dentistry · 2024

A 42-year-old patient has hepatosplenomegaly and asymmetric enlargement of lymph nodes in the neck area (painless, medium density). Histology of a lymph node revealed giant cells with a large multilobed nucleus, textured nucleoli, and wide eosinophilic cytoplasm (Reed-Sternberg cells), as well as cells with two "mirrored"nuclei, each of which contains an acidophilic nucleolus surrounded by a clear zone ("owl’s eye"). What is the most likely diagnosis in this case?

Answer options

  1. Chronic lymphocytic leukemia
  2. Lymphogranulomatosis
  3. Burkitt lymphoma
  4. Acute lymphoblastic leukemia
  5. Non-Hodgkin lymphoma
Correct answer

Lymphogranulomatosis

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