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Exam questionKROK 1Medicine ยท 2003

Methotrexate (structural analogue of the folic acid which is competitive inhibitor of the dihydrofolatreductase) is prescribed for treatment of the malignant tumour.On which level does methotrexate inhibit synthesis of the nucleic acids?

Answer options

  1. Replication
  2. Transcription
  3. Processing
  4. Mononucleotide synthesis
  5. Reparation
Correct answer

Mononucleotide synthesis

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