A 55-year-old patient with continuing ventricular arrhythmias was admitted to the hospital. The patient is taking timolol drops for glaucoma, daily insulin injections for diabetes mellitus, and an ACE inhibitor for hypertension. You have decided to use phenytoin instead of procainamide. What is the reason?

Answer options

1. The cholinergic effects of procainamide would aggravate the diabetes
2. The anticholinergic effect of procainamide would aggravate glaucoma
3. The hypertensive effects of procainamide would aggravate the hypertension
4. The local anesthetic effect of procainamide would potentiate diabetes
5. The local anesthetic effect of procainamide would aggravate the hypertension