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Exam questionKROK 1Medicine ยท 2005

Methotrexate (structural analogue of the folic acid which is competitive inhibitor of the dihydrofolatreductase) is prescribed for treatment of the malignant tumour. On which level does methotrexate hinder synthesis of the nucleic acids?

Answer options

  1. Replication
  2. Processing
  3. Reparation
  4. Mononucleotide synthesis
  5. Transcription
Correct answer

Mononucleotide synthesis

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