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Exam questionKROK 1Medicine ยท 2006

Increased fragility of vessels, enamel and dentine destruction resulting from scurvy are caused by disorder of collagen maturation. What stage of procollagen modification is disturbed under this avitaminosis?

Answer options

  1. Formation of polypeptide chains
  2. Removal of C-ended peptide from procollagen
  3. Hydroxylation of proline
  4. Detaching of N-ended peptide
  5. Glycosylation of hydroxylysine residues
Correct answer

Hydroxylation of proline

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