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Exam questionKROK 1Medicine ยท 2008

Parents of a 3-year-old child have been giving him antibiotics with purpose of preventing enteric infections for a long time. A month later the child's condition changed for the worse. Blood examination revealed apparent leukopenia and granulocytopenia. What is the most probable mechanism of blood changes?

Answer options

  1. Autoimmune
  2. Redistributive
  3. Age-specific
  4. Hemolytic
  5. Myelotoxic
Correct answer

Myelotoxic

Explanation

Bone marrow suppression is also known as myelotoxicity or myelosuppression is the decrease in the production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes). It can be caused by NSAIDs and many other drugs like antibiotics.

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