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Exam questionKROK 1Medicine ยท 2008

During starvation muscle proteins break up into free amino acids. These compounds will be the most probably involved into the following process:

Answer options

  1. Gluconeogenesis in liver
  2. Synthesis of higher fatty acids
  3. Gluconeogenesis in muscles
  4. Decarboxylation
  5. Glycogenolysis
Correct answer

Gluconeogenesis in liver

Explanation

Gluconeogenesis (GNG) is a metabolic pathway that results in the generation of glucose from certain non-carbohydrate carbon substrates. Gluconeogenesis occurs mainly in the liver and in a lesser extent, in the cortex of the kidneys. The precursors of gluconeogenesis are lactate, glycerol, amino acids, and propionate making a minor contribution. The gluconeogenesis pathway consumes ATP, which is derived primarily from the oxidation of fatty acids.

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