A patient ill with neurodermatitis has been taking prednisolone for a long time. Examination revealed high rate of sugar in his blood. This complication is caused by the drug influence upon the following link of carbohydrate metabolism:

Answer options

1. Activation of insulin decomposition
2. Inhibition of glycogen synthesis
3. Gluconeogenesis activation
4. Intensification of glucose absorption in the bowels
5. Glycogenogenesis activation

Explanation

Glucocorticoids (prednisolone) stimulate (activate) gluconeogenesis increasing blood sugar levels and lipolysis.