A patient with frequent attacks of stenocardia was prescribed sustak-forte to be taken one tablet twice a day. At first the effect was positive but on the second day stenocardia attacks resumed. What can explain inefficiency of the prescribed drug?

Answer options

1. Cumulation
2. Idiosyncrasy
3. Dependence
4. Tachyphylaxis
5. Sensibilization

Explanation

Tachyphylaxis is a quick weakening of the effect, sometimes may occur after first drug introduction (usually connected with substrate exhaustion). In other words, it is a medical term describing an acute, sudden decrease in response to a drug after its administration.