Exam questionKROK 1Medicine ยท 2008
A 7-year-old child is ill with bronchitis. It is necessary to administer him an antibacterial drug. What drug of fluoroquinolone group is CONTRAINDICATED at this age?
Answer options
- Ampiox
- Cyprofloxacin
- Ampicillin
- Sulfadimethoxine
- Amoxicillin
Correct answer
Cyprofloxacin
Explanation
Ciprofloxacin is a fluoroquinolone (antibiotics) that inhibits prokaryotic enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. They are bactericidal and must not be taken with antacids. They are also contraindicated in pregnant women, nursing mothers, and children.
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