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Exam questionKROK 1Medicine ยท 2008

Myocyte cytoplasm contains a big number of dissolved metabolites of glucose oxidation. Name one of them that turns directly into a lactate:

Answer options

  1. Oxaloacetate
  2. Glycerophosphate
  3. Fructose 6-phosphate
  4. Glucose 6-phosphate
  5. Pyruvate
Correct answer

Pyruvate

Explanation

When sufficient oxygen is not present in the muscle cells for further oxidation of pyruvate and NADH produced in glycolysis, NAD+ is regenerated from NADH by reduction of pyruvate to lactate. Pyruvate is converted to lactate by the enzyme lactate dehydrogenase.

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