A 46-year-old patient applied to a doctor complaining about joint pain that becomes stronger the day before weather changes. Blood examination revealed strengthened concentration of uric acid. The most probable cause of the disease is the intensified disintegration of the following substance:

Answer options

1. Uridine triphosphate
2. Uridine monophosphate
3. Adenosine monophosphate
4. Thymidine monophosphate
5. Cytidine monophosphate

Explanation

In a catabolic pathway, adenosine monophosphate can be converted to uric acid, which is excreted from the body in mammals. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. High blood concentrations of uric acid can lead to gout as in the above case.