Exam questionKROK 1Medicine ยท 2008
A 38-year-old patient suffers from rheumatism in its active phase. What laboratory characteristic of blood serum is of diagnostic importance in case of this pathology?
Answer options
- Creatinine
- Uric acid
- Urea
- C-reactive protein
- Transferrin
Correct answer
C-reactive protein
Explanation
A 38 year old patient suffers from rheumatism in its active phase. What laboratory characteristic of blood serum is of diagnostic importance in case of this pathology?C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, whose levels rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells. CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes).
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