Exam questionKROK 1Medicine ยท 2008
Examination of a young woman revealed a node-like, soft and elastic homogenous tumour of pinkish-white colour along the acoustic nerve. The tumour contains cell bundles with oval nuclei. Cellular fibrous bundles form rhythmic structures made up by parallel rows of regularly oriented cells arranged in form of a palisade with cell-free homogenous zone (Verocay bodies) between them. What tumour is it?
Answer options
- Malignant neurinoma
- Ganglioneuroblastoma
- Neurinoma
- Ganglioneurinoma
- Neuroblastoma
Correct answer
Neurinoma
Explanation
Neurinoma, acoustic (schwannoma) is a benign tumor that may develop on the hearing and balance nerves near the inner ear. The tumor results from an overproduction of Schwann cells -- small sheet-like cells that normally wrap around nerve fibers like onion skin and help support the nerves. Verocay ("Antoni A") bodies are cellular areas surrounded by nuclear palisades (as opposed to less cellular "Antoni B"). This histological pattern is found in Schwannoma neoplasms.
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