Exam questionKROK 1Medicine ยท 2008
Autopsy of a man ill with severe hypothyroidism revealed that connective tissue, organ stroma, adipose and cartilaginous tissues were swollen, semitransparent, mucus-like. Microscopic examination of tissues revealed stellate cells having processes with mucus between them. What type of dystrophy is it?
Answer options
- Stromal-vascular adipose
- Parenchymatous proteinaceous
- Stromal-vascular carbohydrate
- Stromal-vascular proteinaceous
- Parenchymatous adipose
Correct answer
Stromal-vascular carbohydrate
Explanation
Stromal vascular carbohydrate degenerations develop due to disturbance of glycosaminoglycans and glycoproteins metabolism. When glycoprotein metabolism is disturbed, chronotropic substances are released from the protein bonds. They accumulate in the main substance of the connective tissue. Collagen fibers change into mucus-like mass. The condition results in colliquative necrosis with the formation of cavities filled with mucus.
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