A 62 year woman complains of frequent pain attacks in the area of her chest and backbone, rib fractures. Her doctor suspected myeloma (plasmocytoma). What of the following laboratory characteristics will be of the greatest diagnostic importance?

Answer options

1. Hypoglobulinemia
2. Hyperalbuminemia
3. Paraproteinemia
4. Proteinuria
5. Hypoproteinemia

Explanation

A paraprotein or myeloma or Plasmacytoma protein is an abnormal immunoglobulin fragment that is produced in excess by an abnormal monoclonal proliferation of plasma cells. Bence Jones Protein are light chains that are excreted in the urine associated with plasma cell malignancies (myeloma) and Waldenstrom macroglobulinemia.