A patient has a decreased vasopressin synthesis that causes polyuria and as a result of it evident organism dehydratati-on. What is the mechanism of polyuria development?

Answer options

1. Acceleration of glomerular filtration
2. Reduced tubular reabsorption of Na ions
3. Reduced tubular reabsorption of protein
4. Reduced tubular reabsorption of water
5. Reduced glucose reabsorption

Explanation

Vasopressin causes low diuresis due to increased reabsorption of water leading to increased blood pressure. Hence its decrease will cause reduced tubular reabsorption of water leading to polyuria.