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Exam questionKROK 1Medicine · 2010

Examination of a 42-year-old patient revealed a tumour of adenohypophysis. Objectively: the patient's weight is 117 kg, he has moon-like hyperemic face, red-blue striae of skin distension on his belly. Osteoporosis and muscle dystrophy are present. AP is 210/140 mm Hg. What is the most probable diagnosis?

Answer options

  1. Cushing’s disease
  2. Essential hypertension
  3. Cushing’s syndrome
  4. Diabetes mellitus
  5. Conn’s disease
Correct answer

Cushing’s disease

Explanation

Moon-like hyperemic face, skin distension on the belly, osteoporosis, muscle dystrophy, and high arterial blood pressure are key signs of Cushing’s.The difference between Cushing's Disease and Syndrome is that Cushing’s syndrome occurs when the body produces too much cortisol while Cushing’s disease occurs when a tumor on the pituitary gland causes the gland to produce too much ACTH, the hormone responsible for cortisol production.

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