A 4-year-old child with hereditary renal lesion has signs of rickets, vitamin D concentration in blood is normal. What is the most probable cause of rickets development?

Answer options

1. Increased excretion of calcium
2. Impaired synthesis of calcitriol
3. Hyperfunction of parathyroid glands
4. Lack of calcium in food
5. Hypofunction of parathyroid glands

Explanation

A 4-year-old child with hereditary renal lesion has signs of rickets; vitamin D concentration in blood is normal. What is the most probable cause of rickets development?In this child, Vitamin D is normal in the blood. Calcitriol (dihydroxycholecalciferol) is produced in the kidneys, and it increases blood calcium level… The renal lesion leading to reduced calcitriol and reduced blood calcium is the primary cause of this rickets.