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Exam questionKROK 1Medicine ยท 2012

A patient suffering from chronic myeloleukemia has got the following symptoms of anemia: decreased number of erythrocytes and low haemoglobin concentration, oxyphilic and polychromatophilic normocytes, microcytes. What is the leading pathogenetic mechanism of anemia development?

Answer options

  1. Deficiency of vitamin B12
  2. Reduced synthesis of erythropoietin
  3. Substitution of haemoblast
  4. Intravascular hemolysis of erythrocytes
  5. Chronic haemorrhage
Correct answer

Substitution of haemoblast

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