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Exam questionKROK 1Medicine ยท 2013

A 60-year-old patient with a long history of stenocardia takes coronarodilator agents. He has also been administered acetylsalicylic acid to reduce platelet aggregation. What is the mechanism of antiplatelet action of acetylsalicylic acid?

Answer options

  1. It has membrane stabilizing effect
  2. It reduces the activity of phosphodiesterase
  3. It enhances the synthesis of prostacyclin
  4. It reduces the activity of cyclooxygenase
  5. It enhances the activity of platelet adenylate cyclase
Correct answer

It reduces the activity of cyclooxygenase

Explanation

It reduces the activity of cyclooxygenase B. It reduces the activity of phosphodiesterase. Acetylsalicylic acid inhibits d activity of cyclooxygenase B.

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