Exam questionKROK 1Medicine ยท 2013
A patient with a dislocated shoulder had been admitted to a hospital. With the purpose of skeletal muscle relaxation he was given an injection of relaxant dithylinum acting normally 5-7 minutes. However, the effect of dithylinum in this patient lasted up to 8 hours. What is the most likely cause of the prolonged effect of dithylinum in this patient?
Answer options
- Material accumulation of the drug
- Genetic deficiency of blood cholinesterase
- Potentiation by another drug
- Reduced drug excretion
- Reduced activity of microsomal liver enzymes
Correct answer
Genetic deficiency of blood cholinesterase
Explanation
Dithyilinum is a myorelaxant which destroys pseudocholinesterase and breaks down into choline and succinic acid.
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