A 50-year-old patient has been administered laevomycetin for the treatment of typhoid fever, but on the next day the patient's condition worsened, the temperature rose to 39,6°C. The deterioration of the patient's condition can be explained by:

Answer options

1. Insensitivity of the pathogen to laevomycetin
2. Re-infection
3. Allergic reaction
4. Secondary infection
5. Effects of endotoxins of the causative agent

Explanation

Laevomycetin is a Bactericidal drug, when it kills the bacteria, its cell wall breaks down and the endotoxins contained in the bacteria are released into the blood therefore causing such reaction.