A patient underwent biopsy of the soft palate arches for a suspected tumor (macroscopy revealed an ulcer with a dense floor). Study of the biopsy material revealed mucosal necrosis with infiltration of lymphocytes, epithelioid cells, plasma cells, single neutrophils in the submucosa. There were also apparent signs of endovasculitis and perivasculitis. The described changes are typical for:

Answer options

1. Necrotizing ulcerative Vincent stomatitis
2. Pharyngeal diphtheria
3. Aphthous stomatitis
4. Primary syphilis
5. Ulcerative stomatitis

Explanation

A patient underwent biopsy of the soft palate arches for a suspected tumor (macroscopy revealed an ulcer with a dense floor). Study of the biopsy material revealed mucosal necrosis with infiltration of lymphocytes, epithelioid cells, plasma cells, single neutrophils in the submucosa. There were also apparent signs of endovasculitis and perivasculitis. The described changes are typical for: The bolded sentence describes a “Hard Chancre” which is the characteristic sign of Primary Syphilis.