A child cut his leg with a piece of glass while playing and was brought to the clinic for the injection of tetanus toxoid. In order to prevent the development of anaphylactic shock the serum was administered by Bezredka method. What mechanism underlies this method of desensitization of the body?

Answer options

1. Stimulation of immune tolerance to the antigen
2. Stimulation of the synthesis of antigen-specific IgG
3. Blocking the mediator synthesis in the mast cells
4. Binding of IgE receptors to the mast cells
5. Binding of IgE fixed to the mast cells

Explanation

Anaphylactic shock occurs when IgE is released in the blood which causes immediate-type hypersensitivity, Bezredka method of administering the toxoid would bind it to the mast cells thereby reducing its release.