Microscopy of the myocardium of a patient who had died from heart failure revealed foci of fibrinoid necrosis located diffusely in the interstitial stroma, and often around the vessels. Such foci were surrounded by lymphocytes, macrophages, histiocytes. Pericardium was found to have signs of sero-fibrinous pericarditis. What is the most likely diagnosis?

Question

Answer options

Myocardial infarction
Rheumatic heart disease
Cardiosclerosis
Cardiomyopathy
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Correct answer

Rheumatic heart disease

Explanation

Rheumatic heart disease is a chronic heart condition caused by rheumatic fever caused by Streptococcus. Macrophages will only be found when there’s something to be engulfed. The other diseases aren’t caused by a pathogen.

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