A patient with signs of osteoporosis and urolithiasis has been admitted to the endocrinology department. Blood test revealed hypercalcemia and hypophosphatemia. These changes are associated with abnormal synthesis of the following hormone:

Answer options

1. Parathyroid hormone
2. Calcitriol
3. Aldosterone
4. Calcitonin
5. Cortisol

Explanation

PTH (parathyroid hormone) increases blood calcium levels by stimulating osteoclasts to break down bone and release calcium. It is also an inhibitor of proximal tubular reabsorption of phosphorus. When there is the production of PTH, there hypercalcemia and hypophosphatemia.