A female patient saught medical-genetic consultation. Physical examination revealed pterygium colli deformity (webbed neck), broad chest, underdeveloped breasts. Study of buccal epithelium cells revealed no X-chromatin in the nuclei. This indicates that the patient has the following syndrome:

Answer options

1. Turner’s
2. Patau’s
3. Down’s
4. Edwards’
5. Klinefelter’s

Explanation

Turner syndrome ( 45 X0 no Barr body) is a chromosomal condition that affects development in females. The most common feature of Turner syndrome is an early loss of ovarian function (ovarian hypofunction or premature ovarian failure) such as a broad chest, underdeveloped breasts.