During blood transfusion a patient has developed intravascular erythrocyte hemolysis. What kind of hypersensitivity does the patient have?

Answer options

1. III type (immune complex)
2. IV type (cellular cytotoxicity)
3. I type (anaphylactic)
4. IV type (granulomatosis)
5. II type (antibody-dependent)

Explanation

type 2 AKA Complement(Antibody) dependent reactions: Antibody is directed against an antigen on cells (such as circulating red blood cells) or extracellular materials (basement membrane). The resulting Ag-Ab complexes activate complement (via the classic pathway), leading to cell lysis or extracellular tissue damage.