A 28-year-old patient undergoing treatment in the pulmonological department has been diagnosed with pulmonary emphysema caused by splitting of alveolar septum by tissular tripsin. The disease is cased by the congenital deficiency of the following protein:

Answer options

1. α2-macroglobulin
2. Transferrin
3. Cryoglobulin
4. Haptoglobin
5. α1-protease inhibitor

Explanation

Alpha 1-antitrypsin is also referred to as alpha-1 proteinase inhibitor (A1PI) because it inhibits a wide variety of proteases. It protects tissues from enzymes of inflammatory cells, especially neutrophil elastase and trypsin.