Parents of 5-year-old child report him o have frequent colds that develop into pneumonia, presence of purulent rashes on the skin. Laboratory tests have revealed the following: absence of immunoglobulins of any type, and naked cells are absent from the lymph nodes punctate. What kind of immune disorder is it?

Answer options

1. Hypoplastic anemia
2. Autosomal recessive agammaglobulinaemia (Swiss type)
3. X-linked hypogammaglobulinemia (Bruton type agammaglobulinemia)
4. Louis-Barr syndrome
5. Agranulocytosis

Explanation

The absence of Ig removes "Hypoplastic anemia", "Agranulocytosis" and "Louis-Barr syndrome". Bruton’s type is just a deficiency of humoral immunity (B lymphocytes). So the symptoms are less severe than Swiss-type which is a deficiency of both humoral and cellular immunity. The patient will start showing symptoms for like 5 months.