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Exam questionKROK 1Medicine ยท 2014

Tissue sampling of a 37-year-old male patient with chronic renal disease has revealed the following: sclerosis, lymphocytic and plasmocytic infiltration of renal pelvis and calices walls, dystrophy and atrophy of tubules. Remaining tubules are enlarged and stretched with colloid masses, epithelium is flattened out ("scutiform"or "shield-shaped"kidney). What is the most likely diagnosis?

Answer options

  1. Tubular interstitial nephritis
  2. Nephrosclerosis
  3. Chronic pyelonephritis
  4. Glomerulonephritis
  5. Acute pyelonephritis
Correct answer

Chronic pyelonephritis

Explanation

No haematuria that removes "Glomerulonephritis". No history of drug or anything that could harm the interstitial, that removes "Tubular interstitial nephritis". It is chronic, which removes "Acute pyelonephritis". No history of hypertension, so "Nephrosclerosis" is out. There was sclerosis, lymphocytic, and plasmacytic infiltration on renal (pelvis) suggests pyelonephritis (chronic renal disease) shows the disease is chronic.

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