It has been found out that one of a pesticide components is sodium arsenate that blocks lipoic acid. Which enzyme activity is impaired by this pesticide?

Question

Answer options

Glutathione reductase
Microsomal oxidation
Glutathione peroxidase
Pyruvate dehydrogenase complex
Methemoglobin reductase

Correct answer

Pyruvate dehydrogenase complex

Explanation

Pyruvate dehydrogenase converts pyruvate to acetyl-CoA in the CA cycle. It acts on pyruvate and lipoic acid. So sodium arsenate has to impair this enzyme complex.

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