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Exam questionKROK 1Medicine ยท 2014

Prolonged fasting causes hypoglycemia which is amplified by alcohol consumption, as the following process is inhibited:

Answer options

  1. Gluconeogenesis
  2. Glycogenolysis
  3. Lipolysis
  4. Proteolysis
  5. Glycolysis
Correct answer

Gluconeogenesis

Explanation

Prolonged fasting causes hypoglycemia which is amplified by alcohol consumption, as the following process is inhibited:Alcohol consumption causes the accumulation of NADH. Due to this, pyruvate is converted to lactate instead of acetyl CoA which is supposed to be the first enzyme of gluconeogenesis. So this is how the process is impaired.

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