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Exam questionKROK 1Medicine ยท 2014

A patient with homogentisuria has signs of arthritis, ochronosis. In this case, the pain in the joints is associated with the deposition of:

Answer options

  1. Oxalates
  2. Homogentisates
  3. Carbonates
  4. Phosphates
  5. Urates
Correct answer

Homogentisates

Explanation

Homogentisuria is the accumulation of homogentisic acid in the urine (alkaptonuria) due to homogentisate 1,2 dioxygenase that helps in the catabolism of phenylalanine and tyrosine.

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