Exam questionKROK 1Medicine ยท 2014
A patient with homogentisuria has signs of arthritis, ochronosis. In this case, the pain in the joints is associated with the deposition of:
Answer options
- Oxalates
- Homogentisates
- Carbonates
- Phosphates
- Urates
Correct answer
Homogentisates
Explanation
Homogentisuria is the accumulation of homogentisic acid in the urine (alkaptonuria) due to homogentisate 1,2 dioxygenase that helps in the catabolism of phenylalanine and tyrosine.
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