Exam questionKROK 1Medicine ยท 2014
Degenerative changes in posterior and lateral columns of spinal cord (funicular myelosis) caused by methylmalonic acid accumulation occur in patients with B12 -deficiency anemia. This results in synthesis disruption of the following substance:
Answer options
- Serotonin
- Dopamine
- Myelin
- Acetylcholine
- Norepinephrine
Correct answer
Myelin
Explanation
B12 is responsible for cell regeneration, Therefore deficiency of it causes degeneration of cells. Note that Myelin sheath is the covering of the Spinal Cord.
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