A patient with signs of emotional lability that result in troubled sleep has been prescribed nitrazepam. Specify the sleep-inducing mechanism of this drug:

Answer options

1. GABA-ergic system activation
2. Supression of serotonergic neurotransmission
3. Inhibition of stimulating amino acids
4. H1-histamine receptors stimulation
5. Blockade of opiate receptors

Explanation

nitrazepam act on benzodiazepine receptors in the brain which are associated with the GABA receptors, causing an enhanced binding of GABA to GABA receptors.