Exam questionKROK 1Medicine ยท 2014
Disruption of nerve fiber myelinogenesis causes neurological disorders and mental retardation. These symptoms are typical for hereditary and acquired alterations in the metabolism of:
Answer options
- Cholesterol
- Sphingolipids
- Higher fatty acids
- Neutral fats
- Phosphatidic acid
Correct answer
Sphingolipids
Explanation
Sphingolipids, a family of membrane lipids, are bioactive molecules that participate in diverse functions controlling fundamental cellular processes such as cell division, differentiation, and cell death. Sphingolipidoses, or disorders of sphingolipid metabolism, have a particular impact on neural tissue.
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