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Exam questionKROK 1Medicine ยท 2015

According to the results of glucose tolerance test a patient has no disorder of carbohydrate tolerance. Despite that glucose is detected in the patients's urine (5 mmol/l). The patient has been diagnosed with renal diabetes. What renal changes cause glucosuria in this case?

Answer options

  1. Increased activity of glucose reabsorption enzymes
  2. Exceeded glucose reabsorption threshold
  3. Decreased activity of glucose reabsorption enzymes
  4. Increased glucose secretion
  5. Increased glucose filtration
Correct answer

Decreased activity of glucose reabsorption enzymes

Explanation

On the decreased activity of glucose reabsorption enzymes in the kidney, it makes it difficult for the kidney to reabsorb glucose back into the blood after filtration, leading to glucosuria.

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