During blood transfusion a patient has developed intravascular erythrocyte hemolysis. What kind of hypersensitivity does the patient have?

Answer options

1. II type (antibody-dependent)
2. III type (immune complex)
3. IV type (cellular cytotoxicity)
4. IV type (granulomatosis)
5. I type (anaphylactic)

Explanation

type 2 AKA Complement(Antibody) dependent reactions: Antibody is directed against an antigen on cells (such as circulating red blood cells) or extracellular materials (basement membrane). The resulting Ag-Ab complexes activate complement (via the classic pathway), leading to cell lysis or extracellular tissue damage.