A 67-year-old patient with clinical diagnosis of chronic bronchitis, pneumosclerosis, and cardiopulmonary decompensation has the biopsy material taken from the suspicious area in his right bronchus mucosa. Cellular and tissue atypi-sm along with pearly bodies can be histologically detected. What pathologic process is characterized by the described histological changes?

Answer options

1. Squamous cell carcinoma of bronchus with keratinization
2. Squamous cell metaplasia of bronchial mucosa
3. Polypoid chronic bronchitis
4. Acute bronchitis
5. Bronchiectasis

Explanation

Squamous cell carcinoma of bronchus with keratinization has more irregular tumor islands infiltration, a greater degree of cellular atypia, atypical mitotic figures, and individual cell keratinization as well as keratin pearl formation.