In case of alkaptonuria, homogentisic acid is excreted in urine in large amounts. The development of this disease is associated with metabolic disorder of the following amino acid:

Answer options

1. Alanine
2. Methionine
3. Phenylalanine
4. Tyrosine
5. Asparagine

Explanation

In alkaptonuria, the enzyme (homogentisate 1,2- dioxygenase) is involved in the metabolism of phenylalanine and tyrosine. And also tyrosine is a product of phenylalanine. So, there’s excess tyrosine. So the RIGHT ANSWER IS "Tyrosine".