A 16-year-old adolescent is diagnosed with hereditary UDP (uridine diphosphate) glucuronyltransferase deficiency. Laboratory tests revealed hyperbilirubinemia caused mostly by increased blood content of the following substance:

Answer options

1. Urobilinogen
2. Biliverdine
3. Stercobilinogen
4. Unconjugated bilirubin
5. Conjugated bilirubin

Explanation

UDP glucuronyltransferase deficiency leads to an increase in unconjugated bilirubin since the enzyme converts unconjugated bilirubin to conjugated bilirubin.