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Exam questionKROK 1Medicine ยท 2015

Biochemical analysis of an infant's erythrocytes revealed evident glutathione peroxidase deficiency and low concentration of reduced glutathione. What pathological condition can develop in this infant?

Answer options

  1. Pernicious anemia
  2. Iron-deficiency anemia
  3. Sicklemia
  4. Megaloblastic anemia
  5. Hemolytic anemia
Correct answer

Hemolytic anemia

Explanation

Glutathione peroxidase deficiency results in a build-up of glutathione which causes hemolysis with oxidative distress. It is a tripeptide of Glycine, Cysteine, and Glutamate.

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