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Exam questionKROK 1Medicine · 2015

An HIV-positive patient's cause of death is acute pulmonary insufficiency resulting from pneumonia. Pathohistological investigation of lungs has revealed interstitial pneumonia, alveolocyte desquamation and methamorphoses: alveolocyte enlargement, large intranuclear inclusions surrounded by lightly-coloured areas. Transformed cells resemble owl's eye. Name the causative agent of pneumonia:

Answer options

  1. Candida fungi
  2. Toxoplasma
  3. Influenza virus
  4. Pneumococcus
  5. Cytomegalovirus
Correct answer

Cytomegalovirus

Explanation

An HIV-positive patient's cause of death is acute pulmonary insufficiency resulting from pneumonia. Pathohistological investigation of lungs has revealed interstitial pneumonia, alveolocyte desquamation and methamorphoses: alveolocyte enlargement, large intranuclear inclusions surrounded by lightly-coloured areas. Transformed cells resemble owl's eye. Name the causative agent of pneumonia: Cytomegalovirus (CMV) produces typical owl’s eye intranuclear inclusion bodies in infected cells.

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