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Exam questionKROK 1Medicine ยท 2015

A patient visited a dentist to extract a tooth. After the tooth had been extracted, bleeding from the tooth socket continued for 15 minutes. Anamnesis states that the patient suffers from active chronic hepatitis. What phenomenon can extend the time of hemorrhage?

Answer options

  1. Decrease of albumine content in blood
  2. Increased activity of anticoagulation system
  3. Decrease of fibrinogen content in blood
  4. Hypocalcemia
  5. Thrombocytopenia
Correct answer

Decrease of fibrinogen content in blood

Explanation

A patient visited a dentist to extract a tooth. After the tooth had been extracted, bleeding from the tooth socket continued for 15 minutes. Anamnesis states that the patient suffers from active chronic hepatitis. What phenomenon can extend the time of hemorrhage?Fibrinogen is made and secreted into the blood primarily by liver hepatocyte cells. Hemostasis is intimately related to liver function because most coagulation factors are synthesized by liver parenchymal cells. The extent of coagulation abnormalities depends upon the degree of disturbed liver function. Acute or chronic hepatocellular diseases may display decreases in the vitamin K- dependent factors (prothrombin; factors VII, IX, and X; proteins C and S), Patients with hepatitis may present with the entire spectrum of factor deficiencies and may even develop disseminated intravascular coagulation (DIC) which cause continuous bleeding.

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