Examination of a 56-year-old woman with a history of type 1 diabetes mellitus revealed a disorder of protein metabolism that is manifested by aminoacidemia in the laboratory blood test values, and clinically by the delayed wound healing and decreased synthesis of antibodies. Which of the following mechanisms causes the development of aminoacidemia?

Answer options

1. Increase in the oncotic pressure in the blood plasma
2. Increase in low-density lipoprotein level
3. Increased proteolysis
4. Albuminosis
5. Decrease in the concentration of amino acids in blood

Explanation

Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. An increased proteolysis results in an increase in amino acids in the blood.